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Bio::SeqIO::entrezgene - Entrez Gene ASN1 parser

Author

       Stefan Kirov <skirov@utk.edu>

Description

       This is EntrezGene ASN bioperl parser. It is built on top of Bio::ASN1::EntrezGene, a low level ASN
       parser built by Mingyi Liu (<http://sourceforge.net/projects/egparser>). The easiest way to use it is
       shown above.

       You will get most of the Entrez Gene annotation such as gene symbol, gene name and description, accession
       numbers associated with the gene, etc. Almost all of these are given as  Bio::AnnotationI objects.

       If you need all the data do:

          my $seqio = Bio::SeqIO->new(-format => 'entrezgene',
                                      -file => $file,
                                      -debug => 'on' );
          my ($gene,$genestructure,$uncaptured) = $seqio->next_seq;

       The second variable returned, $genestructure, is a Bio::Cluster::SequenceFamily object. It contains all
       Refseqs and the genomic contigs that are associated with the particular gene. The third variable,
       $uncaptured, is a reference to a plain array.

       You can also modify the output to allow back compatibility with the old LocusLink parser:

          my $seqio = Bio::SeqIO->new(-format => 'entrezgene',
                                      -file => $file,
                                      -locuslink => 'convert');

       The "-debug" and "-locuslink" options slow down the parser.

       Example code which looks for ontology terms:

         my $eio = new Bio::SeqIO(-file => $file,
                                  -format => 'entrezgene',
                                  -service_record => 'yes');

         while (my $seq = $eio->next_seq) {
           my $gid = $seq->accession_number;
           foreach my $ot ($ann->get_Annotations('OntologyTerm')) {
             next if ($ot->term->authority eq 'STS marker'); # No STS markers
             my $evid = $ot->comment;
             $evid =~ s/evidence: //i;
             my @ref = $ot->term->get_references;
             my $id = $ot->identifier;
             my $fid = 'GO:' . sprintf("%07u",$id);
             print join("\t",$gid, $ot->ontology->name, $ot->name, $evid,
               $fid, @ref?$ref[0]->medline:''), "\n";
           }
         }

Feedback

Mailinglists
       User feedback is an integral part of the evolution of this and other Bioperl modules. Send your comments
       and suggestions preferably to the Bioperl mailing list.  Your participation is much appreciated.

         bioperl-l@bioperl.org              - General discussion
         http://bioperl.org/Support.html    - About the mailing lists

   Support
       Please direct usage questions or support issues to the mailing list: bioperl-l@bioperl.org

       rather than to the module maintainer directly. Many experienced and reponsive experts will be able look
       at the problem and quickly address it. Please include a thorough description of the problem with code and
       data examples if at all possible.

   Reportingbugs
       Report bugs to the Bioperl bug tracking system to help us keep track of the bugs and their resolution.
       Bug reports can be submitted via the web:

         https://github.com/bioperl/bio-asn1-entrezgene/issues

Name

       Bio::SeqIO::entrezgene - Entrez Gene ASN1 parser

Synopsis

          use Bio::SeqIO;

          # don't instantiate directly - instead do
          my $seqio = Bio::SeqIO->new(-format => 'entrezgene',
                                      -file => $file);
          my $gene = $seqio->next_seq;

Version

       version 1.73

_Process_Products_Coordinates

       To do:

_Process_Prop

       To do: process GO

See Also