bali-phy - Bayesian Inference of Alignment and Phylogeny
Contents
Description
bali-phy estimates multiple sequence alignments and evolutionary trees from DNA, amino acid, or codon se‐
quences. BAli-Phy uses MCMC and Bayesian methods to estimate evolutionary trees, positive selection, and
branch lengths while averaging over alternative alignments.
BAli-Phy can also estimate phylogenies from a fixed alignment (like MrBayes and BEAST) using substitution
models like GTR+gamma. BAli-Phy automatically estimates relative rates for each gene.
Examples
bali-phydna.fasta--smodelgtr
Analyze sequences in dna.fasta under the GTR model.
bali-phydna.fasta-Sgtr-Inone
Perform a traditional fixed-alignment analysis with gaps treated as missing data.
bali-phydna.fastaamino.fastacodons.fasta-S1:gtr-S2:lg08-S3:gy94
Perform an analysis of 3 genes where each gene has a different substitution mode. The sequence
names in all three files must be the same.
General Options
For each option below, more information is available by specifying the long form of the option as a help
topic. For example: bali-phyhelpalphabet-h, –help, –help=topic
Display a friendly help message. Specify –help=advanced or –help=expert to display more advanced
options.
-v, –version
Print version information.
-t, –test
Analyze the initial values and exit.
-V, –verbose, –verboseNUM
Print extra output to aid in trouble-shooting. If NUM is not specified the default is 1. Values
from 2 to 4 increase the amount of information displayed.
-cfilename, –configfilename
Read commands from filename before command line.
Mcmc Options
-iNUM, –iterationsNUM
The number of iterations to run.
-nSTRING, –nameSTRING
Name for the output directory to create.
-xNUM, –subsampleNUM
Factor by which to subsample. This option should usually not be used.
-sNUM, –seedNUM
Random seed. Useful for replaying specific runs when trouble-shooting.
Model Options
-Aalphabet, –alphabetalphabet
The alphabet.
-Smodel, –smodelmodel
The substitution model.
-Imodel, –imodelmodel
The insertion-deletion model.
-Bprior, –branch-lengthsprior
Prior on branch lengths.
-Rprior, –scaleprior
Prior on the scale.
-LNUMS, –linkNUMS
Link partitions. Takes a comma-separated list of numbers indicating partitions. For example
--link1,2,3.
Name
bali-phy - Bayesian Inference of Alignment and Phylogeny
Parameter Options
-Tfilename, –treefilename
File with initial tree in Newick format or NEXUS format.
-U, –unalign
Unalign all variable-alignment partitions before starting MCMC instead using the supplied align‐
ment as a starting value.
Reporting Bugs
BAli-Phy online help: <http://www.bali-phy.org/docs.php>.
Please send bug reports to <bali-phy-users@googlegroups.com>.
See Also
bp-analyze
Synopsis
bali-physequence-file1 [sequence-file2 ...] [OPTIONS]
bali-phy help topic