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SIFT_for_submitting_fasta_seq.csh - predict effect of an amino acid substitution on protein function

Author

       Pauline Ng

Description

       SIFT predicts whether an amino acid substitution affects protein function based on sequence homology and
       the physical properties of amino acids.

       Results are stored in ./<seq_file>.SIFTprediction.

       This program is used for FASTA input and is part of the SIFT suite.

Examples

        SIFT_for_submitting_fasta_seq.csh /usr/share/doc/sift/examples/lacI.fasta [BLAST_DB] /usr/share/doc/sift/examples/lacI.subst

Name

       SIFT_for_submitting_fasta_seq.csh - predict effect of an amino acid substitution on protein function

Options

       <FASTA_FILE>
           Protein sequence in fasta format.

       <BLAST_DB>
           Protein database to search.  These sequences are assumed to be functional.

       <SUBSTITUTIONS_FILE>
           File of substitutions to be predicted.  See /usr/share/doc/sift/examples/lacI.subst for an example of
           the format.  If you give '-', scores for all mutations of the entire protein sequence are printed.

       [BLAST_PROCESSORS]
           Number of processors/cores to use when running blast via the -a argument.

See Also

       info_on_seqs

4.0.3b                                             2017-12-05               SIFT_FOR_SUBMITTING_FASTA_SEQ.CSH(1)

Synopsis

       SIFT_for_submitting_fasta_seq.csh <FASTA_FILE> <BLAST_DB> <SUBSTITUTIONS_FILE> [BLAST_PROCESSORS]

See Also