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TM-score - an algorithm to calculate the similarity of topologies of two protein structures

Author

       For comments/suggestions,please contact email: zhng@umich.edu.

       This manpage was compiled by Tim Booth (tbooth@ceh.ac.uk)

.                                                  2011-02-03                                         TMSCORE(1)

Description

       This program is to compare two protein structures and identify the best superposition that has the
       highest TM-score. Input structures must be in the PDB format. By default, TM-score is normalized by the
       second protein. Users can obtain a brief instruction by simply running the program without arguments.

Name

       TM-score - an algorithm to calculate the similarity of topologies of two protein structures

Options

-o filename.sup Outputs the superposition to the specified file,
              suitable for use in rasmol.

           -d value Sets d0 to the specified number of angstroms.

See Also

       TMalign, rasmol

       When  using  this proram and for more detailed information, please refer to the publication in
       NucleicAcidsRes.  (2005) Volume 33 page 2303ff. by Zhang and Skolnick.

Synopsis

       1. Run TM-score to compare 'model' and 'native':

           TMscore model native

       2. Run TM-score with an assigned d0, e.g. 5 Angstroms:

           TMscore model native -d 5

       3. Run TM-score with superposition output, e.g. 'TM.sup', and view in Rasmol:

           TMscore model native -o TM.sup
           rasmol -script TM.sup

Version

       This documentation refers to TM-score version released on 2011/01/30

See Also